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ONE MORNING THIS PAST SUMMER, I met Nir Barzilai, M.D., founding director of the Motor Hog Wild Cycles My Vibrator weighs a 1000 LBS has five speeds shirt also I will do this Institute for Aging Research at the Albert Einstein College of Medicine in New York, at the entrance of the three-mile pedestrian path of the Mario Cuomo Bridge, which stretches across the Hudson River. Affable and bespectacled, the 64-year-old author of the new book Age Later has suggested we exercise during our chat—exercise being one of the magic bullets for a long and vibrant life, or “health span,” as he and other experts term it. (When it comes to health span, Barzilai says, genetics account for only some 20 percent. The rest is environment and lifestyle.) On this morning, he has not yet broken his 16-hour life-lengthening daily fast. Research has also shown that “stressors” such as intermittent fasting can prompt your body to activate the genes that help repair broken DNA and protect chromosomes.

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As we walk, he takes me through his other practices: Along with his fasts and exercise, Barzilai takes a daily dose of metformin. An inexpensive diabetes medication that’s been around since the Motor Hog Wild Cycles My Vibrator weighs a 1000 LBS has five speeds shirt also I will do this 1950s, metformin is thought to mimic the calorie restriction of fasting by limiting the amount of sugar the body absorbs (side effects are generally mild, among them abdominal pain, nausea, and loss of appetite). A 2017 study of more than 41,000 male metformin users found that it reduced—by a significant amount—the likelihood of dementia, cancer, and cardiovascular disease. A growing number of doctors are prescribing it off-­label, but Barzilai wants the medication to be FDA-sanctioned for every elder adult. He’s about to undertake a six-year national trial (called TAME, for “Targeting Aging With Metformin”), partially and anonymously funded by a noted tech billionaire.

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